Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders ...

Their method relies on combining fibroblast growth factor 4 (FGF4) with vitamin C, a pairing that accelerates cell maturation and enhances function. "Our findings bring us closer to transforming ...

to now reveal that retinoids treat and prevent acne in part by influencing the behavior and function of fibroblasts. Specifically, they inhibited lipid generation among fibroblasts undergoing ...

Our research focuses on the tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function as well as immune suppression, and how these stromal mechanisms affect cell fate and ...

"We know that during the remodeling process fibroblasts are activated," said ... one week to assess pulmonary hemodynamics and cardiac function. Treatment response was also assessed for patients ...