At present, however, no definitive studies support the premise that PPAR-γ expression is required for anti-inflammatory effects in macrophages. Here, we report that PPAR-γ is not essential for ...

The biotech’s approach to fighting cancer is based around “repolarising” tumour-associated macrophages (TAMs) using small molecule drugs so that they no longer suppress the immune system ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

Currently there are no cures for rheumatoid arthritis (RA ... in-depth investigation of a specific population of cells: 'the macrophages' that reside in the synovium of RA patients, 'individuals ...