However, knockout of the coxsackie and adenovirus receptor (CAR) in LMH cells inhibited the replication of FAdV ... Then, LMH cells were first transfected with gRNA targeting chicken CAR. At 48 h post ...

The oncolytic adenovirus (Adv) exhibited poor infection efficiency in tumor cells with low coxsackie and adenovirus receptor (CAR) on the cell surface, which limits the therapeutic efficacy of the Adv ...

to carry miRNA-124 and all-trans retinoic acid derivative to achieve efficient stem-cell transfection and neural differentiation. TILT-123 is an oncolytic adenovirus encoding TNFα and IL-2.

The global viral vector and plasmid DNA manufacturing market size is calculated at USD 8.66 billion in 2025 and is expected ...

Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...

The recombinant adenovirus-expressing TFF1 was generated by cotransfecting HEK-293 cells with the shuttle and backbone adenoviral (pJM17) plasmids using the Calcium Phosphate Transfection kit (Applied ...

5 Pulmonary and Critical Care Unit and Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Massachusetts, USA 6 Division of ...

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in late 2019 caused coronavirus disease 2019 (COVID-19), which soon became a global pandemic. Efforts to ...