The mechanism of IgM assembly remained incompletely understood. This work demonstrates how J-chain outcompetes the sixth ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

Primary antiphospholipid syndrome (PAPS) is a clotting disorder attributed to autoreactive antibodies produced by B cells. Here the authors show, using single cell omics and B cell repertoire data ...

All patients had an immune response to the vaccine eliciting HER-2-specific antibodies. These antibodies inhibited signal transduction pathways in vitro, as exhibited by inhibition of ...

Monoclonal antibodies (mAbs) are manufactured proteins that behave similarly to antibodies found naturally in the body. Researchers initially developed them for treating certain cancers but have ...

Uppsala University. "New antibody could be promising cancer treatment." ScienceDaily. www.sciencedaily.com / releases / 2024 / 11 / 241111122713.htm (accessed December 2, 2024). Explore More from ...