The mechanism of IgM assembly remained incompletely understood. This work demonstrates how J-chain outcompetes the sixth ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

All patients had an immune response to the vaccine eliciting HER-2-specific antibodies. These antibodies inhibited signal transduction pathways in vitro, as exhibited by inhibition of ...

Monoclonal antibodies (mAbs) are manufactured proteins that behave similarly to antibodies found naturally in the body. Researchers initially developed them for treating certain cancers but have ...

This includes HSV-1, the type most commonly linked to cold sores, and HSV-2, the type mainly associated with genital herpes. The test doesn't detect the virus itself but instead detects ...

"New antibody could be promising cancer treatment." ScienceDaily. www.sciencedaily.com / releases / 2024 / 11 / 241111122713.htm (accessed December 2, 2024). Explore More from ScienceDaily RELATED ...

Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 465-8603, Japan Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural ...

The chimeric B- and T-cell epitope strategy can fully stimulate the immune system to produce high-affinity antibodies that can specifically target cancer cells and, most importantly, establish an ...

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