Watanabe and his team used electron microscopy to examine unmyelinated axons in mice and determine whether the pearled pattern was the natural axon shape. Watanabe began his investigation by exploring ...

On the technical side, our lab uses a number of complementary approaches to identify and study genes controlling axon navigation. Techniques involve genetic screens, RNA interference and CRISPR/Cas9 ...

“These findings challenge a century of understanding about axon structure,” Shigeki Watanabe, study author and associate professor of cell biology and neuroscience at the Johns Hopkins ...