Francis P. Worden, MD, discusses how the effectiveness of lenvatinib in this real-world setting compares with results from ...
引言结直肠癌(CRC)易发生肝转移,初始不可切除结直肠癌肝转移(CRLM)是临床处理中的难点。目前多项指南共识对 CRLM 的治疗做出推荐,同时临床研究结果的出炉也带来更多证据。2024 年 11 月,CAIRO5 研究事后分析结果公布[1],为 ...
BRAF V600E mutations are common in different tumor types (more frequently in melanomas, colon and thyroid carcinomas). BRAF Alterations in Brain Tumors: Different Diagnostic Relevance of BRAF ...
Novartis' two-drug regimen of Tafinlar and Mekinist has been approved by the FDA as the first therapy for solid tumours that have a BRAF V600E mutation – regardless of where they occur in the body.
非小细胞肺癌(NSCLC)是世界上最常见的恶性肿瘤之一。EGFR酪氨酸激酶抑制剂(EGFR-TKI)是表皮生长因子细胞受体突变(EGFR突变型)晚期NSCLC患者的首选一线治疗药物。不幸的是,药物耐药会不可避免地导致疾病进展。ALK和BRAF旁路信号 ...
达拉非尼治疗转移性非小细胞肺癌: 在BRAF V600E突变NSCLC患者中,达拉非尼联合曲美替尼的治疗方案能够显著延长患者的生存期,客观缓解率(ORR ...
非小细胞肺癌(NSCLC)是全球癌症死亡的主要原因之一,其治疗方案的探索与革新始终是全球医疗领域关注的焦点。随着精准医疗时代的到来,针对特定基因突变的靶向疗法以及免疫疗法的兴起,为NSCLC患者带来了前所未有的治疗希望。 除了EGFR和ALK之外,NSCLC ...
Explore the challenges and advancements in anti-EGFR antibody treatment for metastatic colorectal cancer. Discover how ...
and a combination regimen for BRAF V600E-positive colorectal cancer with Pfizer’s Braftovi (encorafenib) and Eli Lilly’s Erbitux (cetuximab). It also covers Novartis’ Mekinist (trametinib ...