二甲双胍是经典的降糖药物，临床应用已有60多年，且具有降糖之外的多种益处，更多治疗潜力还在不断展现中，素有“神药”之誉。这种源自天然草药山羊豆的药物，为何能拥有如此宽泛的功效？尽管目前为止二甲双胍的作用机制尚未完全阐明，但众多证据 ...

The interplay between genetics and weight loss outcomes was highlighted by Wang et al., who identified the CAMKK2 variant as a novel monogenic obesity variant (MOV). Using whole-exome sequencing and ...

Ferroptosis, a new iron- and reactive oxygen species–dependent form of regulated cell death, has attracted much attention in the therapy of various types of tumors. With the development of ...

Phenotypic and genetically predicted leukocyte telomere length and prostate cancer risk: Results from a large-scale longitudinal cohort study. Multivariate logistic regression analyzing association ...

Department of Pharmacy and Institute of Inflammation, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital (X.H., Y.Z., Y.W., G.L.) Zhejiang ...