随着MNC与国内Biotech的BD交易不断涌现，TCE疗法浮出水面，成为医药行业重点押注的赛道。10月31日，艾伯维出手14.65亿美元，押注TCE，与EvolveImmune ...

中国科学院分子细胞科学卓越创新中心（生物化学与细胞生物学研究所）许琛琦研究组联合上海科技大学王皞鹏研究组，在 Immunity 期刊发表了题为 Phase separation of chimeric antigen receptor ...

11月27日，国际学术期刊Immunity在线发表了中国科学院分子细胞科学卓越创新中心 (生物化学与细胞生物学研究所)许琛琦研究组联合上海科技大学王皞鹏研究组的最新合作成果：“Phase?separation of chimeric antigen receptor promotes immunological synapse?maturation and ...

与天然的受体TCR相比，CAR的抗原敏感性差，并且与其它信号分子的协同性差。这些劣势是因为CAR无法像TCR一样形成成熟的免疫突触来整合各条信号通路。这些信号的劣势会导致CAR T细胞无法清除抗原表达量低的靶细胞，并且容易发生功能耗竭，无法长期工作。

Cytotoxic T cells are CD8-postive T cells that are specialized for the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the ...

The Raman and Athar team's study uncovered that the lymphocyte cell surface protein CD2 is expressed at elevated levels on T lymphocytes and innate lymphocytes, including natural killer cells (NK ...

Tesla’s top battery cell supplier, CATL, is throwing some cold water on Tesla’s battery plans and the CEO even said that Elon Musk “doesn’t know how to make battery cells.” Contemporary ...

He also explained that things have been cordial between both campaigns. "We haven't seen anything thus far that would indicate that there's going to be any overturning of this race, but the Therriault ...

Called Vance, the global, multinational, randomised phase three trial, led by Singapore clinician-scientist Toh Han Chong, is the largest completed trial on T-cell therapy on any solid tumour.

In a pivotal congressional race in Maine, the state's ranked choice voting system is being used this week to determine the winner, but that won't be the end of it. The currently trailing candidate has ...

ALK- ALCL is negative for cytokeratins and germ cell markers OCT3/4 and SALL4. Poorly differentiated carcinomas are cytokeratin-positive and lack CD30 and T-cell markers, with variable expression of ...