Cytokine-induced killer cells are a heterogeneous cell population that can be expanded ex vivo from PBMC with the addition of IFN-γ, anti-CD3 antibody, and IL-2. In fact, many additional cytokines ...

Leveraging tumor organoids to model drug response in clear cell renal cell carcinoma. % Reactive Fragments 65.2 ± 26.8 43.0 ± 46.2 % CD56 + of TIL Expansion 14.1 ± 26.2 9.8 ± 4.6 % CD3 + of TIL ...

Human NK cells are a subset of peripheral blood lymphocytes defined by the expression of CD56 or CD16 and the absence of the T-cell receptor CD3. NK cells comprise of 10–15% of the lymphocyte ...

Blood and urine were routinely tested. CD4:CD8 ratios were determined and lymphocyte subsets were analyzed using CD3-, CD4-, CD8-, CD19- and CD56-reactive monoclonal antibodies and flow cytometry ...

Hepatocellular carcinoma (HCC) remains an important complication of chronic liver disease, especially when cirrhosis occurs. Existing treatment strategies include surgery, loco-regional techniques, ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

主要包括CD3+和CD56+细胞。 抗肿瘤活性 CIK细胞具有非MHC限制性的杀伤活性，能够识别并杀伤多种类型的肿瘤细胞，包括髓性白血病、黑色素瘤、肾细胞癌、非何杰金氏淋巴瘤等。其抗肿瘤作用主要通过直接细胞毒性和分泌多种细胞因子（如IFN-γ、TNF-α、IL-2等 ...

These cells were stained with antibodies staining CD3, CD56 and other cell surface markers. After fixation and permeabilisation, these cells were stained with fluorochrome-conjugated antibodies ...

Panel D shows CAR detection on CD3+ lymphocytes on flow cytometric analysis ... intracellular antigen and negative for EBER, perforin, CD56, TdT, CD34, and CD1a, with a high Ki-67 proliferation ...

Objectives NFIL3 is a key immunological transcription factor, with knockout mice studies identifying functional roles in multiple immune cell types. Despite the importance of NFIL3, little is known ...

近年来，精准靶向治疗已经成为携带驱动基因晚期非小细胞肺癌（NSCLC）患者的标准治疗方案。间质表皮转化因子 14 外显子跳跃突变（MET ex14 跳突）是 NSCLC 的少见靶点。凭借良好的疗效和安全性表现，MET 抑制剂已获国内外权威指南推荐用于 MET ex14 跳突 NSCLC 患者的治疗。本期「In China For Global - MET 新例量」分享 ...