Background: In people living with HIV (PLHIV), the CD4/CD8 ratio has been proposed as a useful marker for non-AIDS events. However, its predictive ability on mortality over CD4 counts, and the role of ...

EMCs or PBMCs were stained with zombie aqua (live/dead discrimination), anti-CD45 (to exclude non-leucocytes), CD3 (T-cell inclusion), CD4 and CD8. Tissue resident memory cells were identified by ...

Introduction Coeliac disease (CD) is a common immune-mediated condition driven by aberrant adaptive CD4+ T cell responses to gluten. The cytotoxic CD8+ and γδ+ T cell response in the epithelium ...

Our study represents the first attempt to assess the clonal proliferation of TCRVδ subsets by flow cytometry that will allow us to diagnose γδTCL. A total of 19 patients with γδT cell tumors and 11 ...

Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States ...

Additionally, local inflammation initiates the production of chemokines and the recruitment of immune cells, including CD8 + T cells. However, how the recruited immune cells and the chemokine system ...

Panel F shows the CAR+CD4−CD8− T-cell counts in peripheral ... response with no detectable circulating CAR T cells by flow cytometry (sensitivity threshold, 1.0×10 −4).

GaSₓ具有 “重编程” 和 “干扰” ...

【导读】将免疫检查点阻断疗法（ICB）与化疗相结合有望治疗三阴性乳腺癌（TNBC），但对其机理仍不完全清楚。在这项研究中，团队整合了已发表的和新的单细胞RNA测序（scRNA-seq）数据，研究了接受紫杉醇（PTX）、纳布-紫杉醇（Nab-PTX）以 ...