S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

Detection of disseminated cancer cells (DCCs) in the bone marrow (BM) of patients with breast cancer (BC) is a critical predictor of late recurrence and distant metastasis. Conventional therapies ...

The ability of individual cells to maintain a distinct identity and respond to transient environmental signals requires tightly controlled regulation of gene networks. However, how discrete sets of ...

This large biological complexity requires coordination between distinct pro-inflammatory and regulatory cell subsets to respond to infection while maintaining tissue homeostasis. CD4+ T cells play a ...

Objectives To study the biology of the conventional T cells in human enthesis. Methods CD4+ and CD8+ T cells were investigated in 25 enthesis samples using immunofluorescence, cytometrically, bulk ...

However, its predictive ability on mortality over CD4 counts, and the role of CD8+ T-cell counts remain controversial. Methods: We conducted a systematic review and meta-analysis of published studies ...

Researchers at the Francis Crick Institute have shown that water influx is necessary for immune cells called T cells to ...

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make ...

Objectives To study non-metabolic effects of insulin in CD4+ T cells of RA patients. Results In total, 102 new cases of DM were registered, significantly less often in RA patients compared to gout ...

Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of ...