目前，MS 的发病机制仍是医学界亟待解开的谜题。已知它涉及针对髓鞘抗原的自身免疫反应，其中辅助性 T 细胞 4（CD4 + T 细胞），尤其是 Th1 和 Th17 亚群，在推动疾病进展中 “扮演” 着重要角色。然而，细胞毒性 T 细胞 8（CD8 + T 细胞）在 MS 和实验性自身免疫性脑脊髓炎（Experimental Autoimmune ...

Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional ...

Clinical trials planned to begin patient enrollment during 2025 to evaluate Gylden’s T cell Priming (TcP) candidates against Dengue (Phase II) ...

在与癌症的百年抗争中，胰腺癌始终是医学界的"珠穆朗玛峰"。这种被称为"癌王"的疾病，五年生存率长期徘徊在12%以下。但该研究为这场攻坚战带来了革命性突破——一种个性化mRNA疫苗成功激活了持续数年的"长寿"免疫细胞，将患者无复发生存期延长3倍。这项发 ...

(UroToday.com) The 2025 American Society of Clinical Oncology (ASCO) Genitourinary (GU) Annual Symposium held in San ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

CD4:CD8 ratios were determined and lymphocyte subsets ... Before electrofusion, the MHC class I expression and ploidy of the tumor cells were determined by flow cytometry. DCs were generated ...

OVA peptide 即卵清蛋白肽，通常指卵清蛋白（Ovalbumin, OVA）中的特定肽段12。以下是常见的 OVA peptide 及其相关多肽信息 平台声明：该文观点仅代表作者本人，搜狐号系信息发布平台，搜狐仅提供信息存储空间服务。

Based on the immunopathology of psoriasis, we have proposed a model for biologic therapeutic approaches that identifies four mechanistic strategies. [25] A host of targeted immunologic ...

In the direct pathway of allorecognition, intact donor Major Histocompatibility Complex (MHC) molecules are recognised on the surface of donor cells. Conversely, donor MHC can be internalised and ...

1School of Basic Medical Science, Southern Medical University, Guangzhou, China. 2Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. 3Zenith Institute of ...