and CD8-positive suppressor T cells, which restrain certain types of immune response. Tumor-infiltrating T cells are known to encounter chronic antigens and hypoxia, which results in exhaustion ...
Cancer immunotherapy has been revolutionized by targeting specific immune subsets within the tumor microenvironment, where T cells play a pivotal role. Gene-engineered T cell strategies and immune ...
MDNA11 shows significant survival benefits in preclinical glioblastoma models, expanding CD8 + T and NK cells Bizaxofusp selectively targets human tumor cells and immune-suppressive cells, enhancing ...