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生物谷
27 天
Cell:中国博后一作,开发CRISPR-Cas13筛选技术,发现778个人类必需lncRNA
该研究开发了一种基于CRISPR-Cas13的靶向RNA的转录组规模的CRISPR筛选技术,并使用该技术在来自不同组织的5种人类细胞中筛选鉴定了778个必需的lncRNA。
腾讯网
26 天
全新CRISPR-Cas13系统登上《细胞》!筛选出近800个必需lncRNA,“垃圾 ...
目前,对lncRNA的研究受到了低通量的限制。最近,CRISPR筛选能够用于识别功能性的lncRNA,不过基于Cas9酶的CRISPR-Cas9系统在DNA水平上编辑基因时 ...
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