AcrVIB1: The unexpected anti-CRISPR protein that tightens RNA binding
The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, ...
EurekAlert!10d
Refining the CRISPR scissors
The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, ...
Nature21d
A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Subsequently, the CRISPR array is transcribed into a long precursor crRNA, which is further processed into the mature crRNA by Csy4 protein. Finally, this stable Csy4-crRNA complex subsequently ...
mskcc.org3y
CRISPR-Cas and cGAS-STING Surveillance Pathways
Efficient and site-specific genome engineering can be achieved based on programmable nucleic acid cleavage using CRISPR-Cas surveillance complexes. Structure-function studies on single component Cas ...
mskcc.org8d
The Naama Aviram Lab
The Aviram Lab investigates the molecular mechanisms that protect microorganisms from their own pathogenic invaders.
Max Planck Society7y
From restriction enzymes to CRISPR-Cas9
With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA indicate where the DNA can be cut. It is relatively easy for scientists to produce different sequence variants from RNA ...