A new review in Engineering reveals that CRISPR technologies are revolutionizing regenerative medicine. Scientists from ...

Intellia Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Intellia's technology platform specializes in Clustered Regularly Interspaced Short ...

CRISPR/Cas9, a groundbreaking gene-editing technology, holds the potential to transform oilseed production in Kashmir ...

A pre-well-designed model before screening is of great importance to the next validation of the top-hit genes. Comprehensively, genome-wide CRISPR/Cas9 knockout (inhibition) or activation screening ...

A recent review published in the journal Engineering delves into the significant advancements and potential of CRISPR technologies in the field of ...

The signal variability caused by different gRNAs targeting the same gene limits the applications of genome-wide CRISPR/Cas9 knockout screens (81). Joint Analysis of CRISPR/Cas9 Knockout Screens (JACKS ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota produces CRISPR/Cas9-mediated knockout and point mutant mice for researchers.

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.