全方位突破：从抗体优化到基因编辑工具。

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area Delle Scienze 17/A, 43124 Parma, Italy ...

"Unlike the well-known CRISPR gene-editing system, often described as molecular 'scissors,' the newly studied type IV-A CRISPR system does not cut genes. Instead, it uses an RNA-guided 'effector ...

该研究开发了一种基于CRISPR-Cas13的靶向RNA的转录组规模的CRISPR筛选技术，并使用该技术在来自不同组织的5种人类细胞中筛选鉴定了778个必需的lncRNA。

Using CRISPR technology that targets RNA instead of DNA, researchers at New York University and the New York Genome Center searched across the genome and found nearly 800 noncoding RNAs important ...

The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can be used to correct specific defective sections of the genome.

ZUG, Switzerland and BOSTON, Nov. 05, 2024 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious ...

A patient with sickle cell disease died while participating in a clinical trial of a CRISPR-based treatment from Beam Therapeutics, threatening to overshadow early signals of effective gene editing.

Jennifer Doudna, the co-developer of CRISPR, says there’s a “coming revolution” in climate-adapted crops and animals. Jennifer Doudna, one of the inventors of the breakthrough gene-editing ...