在生命科学领域，基因编辑技术的每一次进步都深刻地改变着疾病治疗的未来。近年来，随着科学技术的迅速发展，RNA编辑作为一种新兴的治疗手段，越来越受到与会科学家和产业界的瞩目。与传统的DNA编辑方法相比，RNA编辑具有避免对遗传信息持久性改变的优势，其可逆性和可控性显著提升了基因编辑的安全性。然而，目前大部分RNA编辑技术仅集中在单碱基编辑上，这在一定程度上限制了其临床应用的广泛性。

站在技术代际更替的转折点，三个趋势已清晰可见：RNA编辑将逐步从单碱基修补转向结构重塑，治疗窗口期从胚胎阶段延展至全生命周期，基因药物开发范式从'纠正错误'转向'功能重建'。对于产业界而言，当务之急是建立RNA结构数据库以优化导向设计，开发体内递送系统突破肝脏靶向限制，同时构建动态监测体系防范脱靶风险。这场由中国人引领的基因编辑革命，正在重新定义生物医药创新的全球版图。 返回搜狐，查看更多 ...

( Nanowerk News) The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic ...

在生命科学领域，基因编辑技术的每一次革新都深刻影响着疾病治疗的未来。近年来，随着基因编辑技术的迅速发展，RNA编辑作为一种新兴的治疗方法，受到了科学界和产业界的广泛关注。与传统的DNA编辑相比，RNA编辑避免了对遗传信息的永久改变，具有可逆性和可控性 ...

CRISPR technology, driven by Cas9, redefines gene editing, facilitating targeted DNA modifications that advance genetic ...

countered by anti-CRISPR proteins (Acrs) in phages, which specifically block these bacterial “gene scissors”. Apart from their counter-defensive function, anti-CRISPR proteins hold great ...

The future of medicine with CRISPR and CAR-T therapy, exploring ethical, societal, and accessibility challenges in healthcare ...

Research team from Würzburg and Braunschweig unveils novel anti-CRISPR protein mechanism for precise control of genome editing technologies The CRISPR-Cas gene scissors offer a wide range of ...

combining the 'molecular scissors' gene-editing technology of CRISPR-Cas9 techniques with its own protein engineering and disease knowledge. The JV will focus on discovering and developing new ...

CRISPR protein AcrVIB1, a promising inhibitor whose precise role has not yet been determined. In cooperation with the ...

A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the functions of two genes involved in the metabolism of beans and that could not be ...