After mouse tumor exosome uptake, dendritic cells induce potent CD8 + T-cell–dependent antitumor effects on syngeneic and allogeneic established mouse tumors. Therefore, exosomes represent a ...
The two major T lymphocyte subsets are (1) T helper cells (Th, CD4+) and (2) cytotoxic T cells (CTL, CD8+). CD4 is a glycoprotein expressed on the surface of T helper cells and regulatory T.