Normal T-cells express CD5 but NK (natural killer) cells do not, positioning NK cells as attractive cytotoxicity cells for CD5CAR design. Additionally, CD5 is highly expressed in T-cell acute ...

The T-cell surface glycoprotein CD5, also known as Lymphocyte antigen T1/Leu-1 and LEU1, is phosphorylated on tyrosine residues by LYN, allowing CD5 to create binding sites for PTPN6/SHP-1.

VIPER-101 is built on Vittoria’s proprietary Senza5™ platform, which integrates CD5 gene-editing technology with a rapid five-day manufacturing process. This platform is designed to enhance ...

MB-105 is March Biosciences’ lead program, launched from the Center for Cell and Gene Therapy (Baylor College of Medicine ... MB-105 is a first-in-class autologous CD5-targeted CAR-T cell therapy in ...