For bloodstream infections caused by chromosomal AmpC β-lactamase-producing strains, cefepime may be an appropriate carbapenem-sparing treatment option. Cefepime is supported as an alternative to ...

The boronic acid transition state inhibitors S-02030 and MB-076 were strategically designed to be active against cephalosporinases and carbapenemases, especially KPC (Klebsiella pneumoniae ...

India has developed a novel antibiotic to fight antimicrobial resistance (AMR), as well as a new drug to tackle burden of ...

The FDA has given the green light to Exblifep, based on long-established beta-lactam antibiotic cefepime and a new extended-spectrum beta-lactamase inhibitor (BLI) called enmetazobactam ...

Orchid Pharma Ltd., a vertically integrated pharmaceutical company, has received seven minor observations from the U.S. Food ...

The second day of the 9th "International Symposium on Current Trends in Drug Discovery Research” at CSIR-Central Drug Research Institute, Lucknow, observed important scientific deliberations by ...

Three of these six pathogens are antibiotic-resistant Gram-negative bacteria. Recently, antibacterial drugs against ESBL-producing Gram-negative bacteria accounted for ∼15% (2 out of 13) of all ...

Its lead combination - cefepime-taniborbactam – is being developed in phase 3 trials for complicated urinary tract infections (cUTI), hospital-acquired bacterial pneumonia, and ventilator ...

Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

MRI of the right foot was consistent with osteomyelitis of the distal phalanx of the right great toe and necrotizing deep space infection. The patient was started on vancomycin and cefepime and taken ...

李朴，临床检验诊断学博士，主任技师，硕士研究生导师，现任重庆大学附属江津医院医学检验科主任。李朴博士致力于大数据驱动的生物标志物筛选、诊断与分层的精准模型构建、感染性疾病与恶性肿瘤的早期诊断与分层及其机制研究，擅长医学实验室质量管理及新型检验技术和方 ...

Wockhardt now intends to file a new drug application (NDA) with the USFDA and seek marketing authorisation application with European Medicines Agency (EMA). Zidebactam/Cefepime, or Zaynich, an ...