has attracted extensive attention as an efficient platform for recombinant protein (RP) production. For obtaining a higher protein titer ... tools and methodologies like the CRISPR/Cas9 gene-editing ...

Now, researchers from Japan have found a protein that may do just ... and epithelial cells. The researchers eliminated AP2A1 expression in older cells and overexpressed AP2A1 in young cells ...

Cytoplasmic polyadenylation element-binding protein 4 (CPEB4 ... However, the functional roles of CPEB4 in Renal cell carcinoma (RCC) are still unclear. This study aims to explore the role and ...

Figure 1: Schematic ... comparison of cells constitutively expressing activated signalling proteins with parental cells does not allow primary and secondary changes in gene expression to be ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Objective Since December 2019, a newly identified coronavirus (severe acute respiratory syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan, China. SARS-CoV-2 enters host ...

Necroptosis is the predominant form of neuronal death after ischemic stroke. This study identifies the deubiquitinating enzyme OTUB2 as a novel regulator of the RIPK1-RIPK3-MLKL necroptotic signaling ...

Objective Although counting of circulating tumour cells ... culture condition selection is unlikely. This result highlights the intratumoural heterogeneity and suggests that some circulating clones ...