Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.

Lebanese cannabis oil extract (COE) has been found to provide significant protection against kidney fibrosis caused by folic ...

Subcellular mislocalization of checkpoint controllers is now surfacing as a mechanism of deregulating cell proliferation in cancer. Figure 1: Oncogene Her2/neu-initiated, Akt-mediated p21 Cip1 ...

The results showed that cordycepin significantly inhibited growth factor signaling in multiple cell lines, particularly through the MEK/ERK and PI3K/AKT/mTOR pathways. This inhibition was observed ...

This fundamental study substantially advances our understanding of the role of zinc in metabolism, specifically a newly established clinical link between mutations in the zinc transporter SLC39A5, ...

It involves cell proliferation, migration, differentiation ... it can exert neuroprotective effects through GPCR signaling pathways, including regulating the PI3K/Akt and ERK signaling pathways.

Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC ... The requirement for canonical Wnt/β-catenin signaling in Hh-driven BCC development is increasingly ...

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...

Dec. 9, 2024 — A new study has identified key gene regulators that enable some deafened animals -- including fish and lizards -- to naturally regenerate their hearing. The findings could guide ...