The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...
Elena Shagisultanova, MD, PhD, is working to uncover effective treatments for HER2-positive breast cancer patients by combining different drugs to counteract the cancer cells’ proliferation.
suggesting a role in NK cell exhaustion. TIPE2, a negative regulator of IL-15 signaling, is upregulated in various conditions and suppresses downstream AKT and Ral activation. The absence of TIPE2 ...
The received wisdom said we were built from around 200 types of cell – such as heart muscle or nerve cells. Instead the Human Cell Atlas project has revealed there are thousands of cell types ...
It involves cell proliferation, migration, differentiation ... it can exert neuroprotective effects through GPCR signaling pathways, including regulating the PI3K/Akt and ERK signaling pathways.