How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a family of small, positively charged proteins termed H1, H2A, H2B, H3, and H4 (Van Holde ...

This means that chromosomal DNA must be replicated only once per cell cycle. To ensure that this is the case, bacterial, archaeal and eukaryotic cells have evolved sophisticated regulatory ...

How did humans evolve brains capable of complex language, civilization, and more? The answer could lie in exceptional DNA.

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

How did humans evolve brains capable of complex language, civilization, and more?       The answer could lie in exceptional DNA. Scientists at UC San Francisco found that parts of our chromosomes have ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

Decades ago, researchers showed that Down syndrome (also known as trisomy 21), was caused when individuals carried an extra ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the ...

Blood screening to detect chromosomes offering less protection against age-related brain diseases may warn you of future health problems ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

This valuable work extends previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly strengthens one of ...