A combined pharmacokinetic model was developed and fitted concurrently ... Standard 1-, 2-, and 3-compartment models were fitted to the concentration-time data for the combined intravenous and ...

a population pharmacokinetics model of polymyxin B with the Phoenix NLME program was developed in our study. A total of 151 plasma samples from 50 patients were collected in the present study.

Results: The pharmacokinetics of intravenous fentanyl reflected a 2-compartment model with a clearance of approximately 1.5 L/min. There was moderate (< 50%) between-subject variability (BSV ...

The primary endpoint was to evaluate the safety, tolerability, and pharmacokinetic (PK) profiles of a subcutaneous injection of ... The PK profile of AK111 was well described by a one-compartment ...

Recently published study focused on the evaluation of a novel etomidate analogue, methoxyethyl etomidate hydrochloride (ET-26), in healthy volunteers to assess its safety, tolerability, ...

Mydriatic microdrops are noninferior to standard drops of a diluted mydriatic mixture when used in infants being screened for ROP.

The study of pharmacokinetics (PK ... danofloxacin against Actinobacillus pleuropneumoniae in an in vitro dynamic model emphasized the importance of preventing drug-resistant mutations.

The importance of pharmacokinetic (PK) and pharmacodynamic (PD ... affecting the design and conduct of paediatric pharmacological studies can be overcome using targeted pharmacometric strategies.

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Postdoctoral fellow at School of Pharmacy, University of Waterloo. Ph.D in Pharmacy. RPh. in South Korea.

Tesla TSLA.O launched a redesigned version of its best-selling Model Y crossover in the United States, Canada and Europe on Thursday, weeks after it was first released in China. The refreshed ...