Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area Delle Scienze 17/A, 43124 Parma, Italy ...

College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China ...

Nov. 6, 2024 — The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers have now shown that there is a ...

In Vivo Medicines Editas Medicine and Genevant Sciences entered into a collaboration and nonexclusive license agreement to combine Editas’ CRISPR Cas12a genome editing systems with Genevant’s ...

该工作系统研究了AsCas12f1及其改进型突变体对靶DNA切割过程的动力学分子机制。研究发现，AsCas12f1解旋原间隔区内DNA后，在非靶链DNA上产生缺口（nick）并进行双向外切模式的核酸降解；随后，AsCas12f1把DNA解旋范围扩展到 ...

BERKELEY, Calif., Nov. 20, 2024 (GLOBE NEWSWIRE) -- Caribou Biosciences, Inc. (Nasdaq: CRBU), a leading clinical-stage CRISPR genome-editing biopharmaceutical company, today announced Rachel Haurwitz, ...

11月22日，产学研合作对接暨安徽“双创汇”走进淮北师范大学活动在伯瑞特酒店举行。淮北师范大学党委书记毕明福出席会议并致辞，淮北市委书记汪华东，市领导黄韡、徐胜利、梁龙义出席，省科技厅三级调研员任建松到会指导。

该论文总结了近年来多种基因编辑系统的研究成果。CRISPR-Cas12a系统因其低毒性和高效的编辑能力脱颖而出。与Cas9不同，Cas12a的独特优势包括T富集的PAM序列要求和产生粘性末端的DNA切割方式。这使其在多种微生物中展现出了出色的编辑效果，特别是对那些难以用 ...