A group of chemists at the University at Albany have developed a new method for fast-acting salmonella detection. The test ...

1). CRISPR–Cas12a has a low tolerance for base-pair mismatches between the crRNA and the DNA target sequence. Ensoma applied its knowledge of the protein’s structure to further hone ...

CRISPR-Cas基因编辑技术在基础研究 ... 除了广为人知的II型Cas9蛋白外，V型Cas12家族（如Cas12a至Cas12n）也逐渐被发掘。尽管多种Cas12蛋白已被鉴定 ...

English等人用RNA引导的Cas12a核酸酶来设靶并裂解水凝胶内的特定（但任意）的由用户定义的DNA部分，从而触发对该材料的驱动。为阐明可编程CRISPR ...

II类CRISPR系统中的Cas蛋白因其组成简单、成本低廉等特点，已被广泛开发成多种基因编辑工具。然而，较为常用的Cas9与Cas12a等CRISPR核酸酶通常具有 ...