using BCRP-HAM-Sf9 membrane preparations and cellular assays (Hoechst assay and cytotoxicity assay) were performed on PLB985-BCRP and HEK293-BCRP cell lines overexpressing BCRP. Results: In all assays ...
Dr Navya Verma Cancer is one of the most dreaded diseases of the 21th century and spreading further with continuance and increasing incidence. It is the third leading cause of death worldwide. It is a ...
Cytotoxic T cells are CD8-postive T cells that are specialized for the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the ...
Molecular Cellular Pharmacology Graduate Program, University of Wisconsin-Madison, Madison, USA Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan ...
This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...
Autoimmune bullous diseases are often associated with significant morbidity and some can even cause mortality, if left untreated. Multiple therapies are now available to treat these blistering ...