Here, we have demonstrated the ability of a novel biodegradable dextran based theranostic nanoparticle (NP) to deliver siRNA downregulating PD-L1 in tumors. Optical imaging highlighted the importance ...

Arrowheads show regions devoid of LYVE1 macrophages where F4/80 macrophages are present. Scale bar – 100um Figure 3. Fluid moves from the EOR to the ovary. (a,b) Schematic of dextran injections ...

Institute of Physical and Theoretical Chemistry, TU Graz, Stremayrgase 9, A-8010 Graz, Austria ...

Injections of retrograde tracers, Fluorescein Dextran (FD-3000MW, biotinylated ... we infer that our tracer injections into the cochlea did not alter the somatic structure of auditory efferents as ...

When my co-founder and I started Invoice Home, we wanted to build a business that could grow over time. We noted many inefficiencies while discussing our past experiences working within ...

However, the cell types and mechanisms involved in the CARD9 protective role against inflammation remain unknown. Design We used dextran sulfate sodium (DSS)-induced and adoptive transfer colitis ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

In either case, the RNA structure (whether spliced or unspliced ... RNase inhibitor (NEB, M0314S) and 10% (w/v) Dextran Sulfate (Merck, S4030) (26) on a Hybrislip at 37°C overnight in a humidified ...

State Key Laboratory of Membrane Biology, School of Pharmaceutical Sciences, Tsinghua-Peking Center for Life Sciences, Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology (Ministry ...

Electron microscopic examination revealed no significant morphological changes in the TJ structure of the colonic epithelial cells between age- and sex-matched WT and Cl1-Tg mice. Similarly, ...