Its effect is based on the breaking of the disulfide bridges of mucus glycoproteins ... With these two blocked thiol groups, erdosteine is an inactive prodrug. Erdosteine is stable only in ...

Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, College of Chemistry and Molecular Engineering, Peking University, ...

Erdosteine is a prodrug and metabolite I is the active metabolite of erdosteine owing to its free thiol group. In acute infective exacerbation of chronic bronchitis or chronic obstructive ...