For those dealing with fatty liver disease, there’s welcome news to report. Earlier this year, the United States Food and ...
More than 1,000 different drugs are thought to cause liver damage and one French study estimated the global annual incidence rate of drug-related liver damage as 8 cases per 100,000 inhabitants ...
Drug-induced liver injury (DILI) can present as a chronic phenotype or acute course. However, there is a lack of research on ...
Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...
推荐意见1:明确危险因素可以预防和早期发现ATB-DILI。NAT2慢乙酰化基因型和GSTM1基因变异、高龄、肝炎病毒感染或合并其他急慢性肝病、HIV感染、营养不良和酒精(乙醇)摄入是ATB-DILI的危险因素(2,B)。
Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...
Drug-induced liver injury including cholestasis is another form of acquired liver disease, accounting for approximately 2 to 5% of hospitalizations for jaundice, 10% of cases of hepatitis in all ...
The John C Martin Centre for Liver Research and Innovations, named after the late philanthropist, will focus on non-alcoholic ...
The drugs' cytotoxicity correlated well with all three types of classification reported in the DILIrank dataset, an FDA resource: DILIconcern class, liver injury description, and hepatotoxicity ...
Pyrrolizidine alkaloids (PAs), widely distributed in plants, are known to induce liver failure. Hepatic platelet accumulation ...
Read More: This is The Best Tea For High Blood Pressure, According to a Dietician A study published in JAMA Network Open ...