Nature5 年
Mitochondria–peroxisome connection
This fragmentation was dependent on both the RING domain of MAPL and the presence of the mitochondrial fission GTPase dynamin-related protein-1 (DRP1). Interestingly, however, when the authors ...
来自MSN24 天
Unlocking mitochondrial secrets: New hope for Parkinson’s treatment
In an effort to restore mitochondrial function in Parkinson’s, we targeted a key protein that controls mitochondrial dynamics called dynamin-related protein 1, or Drp1. Naturally abundant in ...
Baylor College of Medicine9 个月
Zhou Lab Publicatations
The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin. FASEB J. 2019 Oct;33(10):11606-11614. doi: 10.1096/fj.201900220R. Epub 2019 Jul 17. PubMed PMID: ...
Mitochondria keep your brain cells alive − helping them run smoothly may protect against ...
In an effort to restore mitochondrial function in Parkinson’s, we targeted a key protein that controls mitochondrial dynamics ...
Business Insider20 天
Walden Biosciences Fully Enrolls First Cohort in Phase 2 Basket Study of WAL0921 in Chronic ...
Walden’s second most advanced program is an IND-ready small molecule that is designed to stabilize and restore the function of dynamin, an enzyme responsible for the maintenance of the cytoskeletal ...