The Warburg effect, which was first described a century ago, asserts that mitotic tumor cells generate higher quantities of lactate. Intriguingly, even in typical physiological circumstances, ...

2019) and fostered the development of several regenerative approaches based on BrM, RPE and photoreceptor cells replacement (Chichagova et al ... removal of the neovascular membrane did not show ...

The 7 major retinal ... edema market are the increasing incidence of diabetic and age-related macular degeneration (AMD), both important causes of this condition. As a result, there is increased need ...

In addition to rod photoreceptor loss ... Identifying mechanisms of cell–cell interactions initiated by rod-specific mutations and affecting other retinal cells is important for understanding ...

Aims To evaluate the recovery of retinal function and the thicknesses of the photoreceptor inner (IS) and outer segment (OS) layers after a reattachment of a rhegmatogenous retinal detachment (RRD).

These include the disruption of outer retinal lamination and a notable decrease as well as mislocalization of photoreceptors, their outer segments, and photoreceptor synapses. Interestingly, despite ...

ARCATUS or ARVN001, in Greater China, South Korea, Australia, New Zealand, India and the ASEAN Countries is formally known as XIPERE in the United States and was developed by Clearside Biomedical.

This involves the covalent attachment of farnesyl or geranylgeranyl residues to cysteines residing in consensus motifs at the C-terminal parts of proteins. Retinal photoreceptor cells are highly ...

(NASDAQ: KPRX) (“Kiora” or the “Company”) today announced it received regulatory approval to initiate KLARITY, a Phase 2 clinical trial to investigate KIO-104 in patients with retinal macular edema, a ...

Here authors show reserpine's disease gene-independent influence on photoreceptor survival ... GCL: ganglion cell layer, *p<0.05. To assess the role of biological sex in P23H molecular pathology, we ...

63 64 RPGRIP1 is a binding partner of retinitis pigmentosa GTPase regulator (RPGR) and is essential for anchoring RPGR at the connecting cilia between the inner and outer segments of photoreceptor ...