As a result, enlarged EEs with abundant intraluminal vesicles (ILVs) accumulate and digestive lysosomes are rudimentary. Together, our results reveal an important and unexpected role of a ...
The phagophore matures into a double-membrane autophagosome that delivers the cargo to the lysosome; lysosomes and autophagosomes fuse to degrade and recycle the cargo. Macroautophagy plays dual ...