Figure 1. Typical pathways of exosome secretion and uptake. Exosomes are produced by sorting mechanism and endosome pathway. After fusion with cell membrane, exosomes are released to the outside of ...

The manuscript presents a useful model for the field of endosome maturation, providing perspective on the role of the deubiquitinating enzyme UPS-50/USP8 in the process. The evidence presented in the ...

The Capital Pathway is one of the most extensive pathway networks in North America. It includes over 200 kilometres of off-road, multi-use pathways, extending from Gatineau Park, through ...

Birth of Jesus; shepherds' adoration; Simeon's and Anna's prophecies; return to Nazareth; Jesus among the doctors; ministry of John the Baptist; baptism of Jesus; genealogy of Jesus through Mary. And ...

Figure 1: The TGN: sorting at the crossroads of the endocytic and exocytic pathways. In addition to ... Interfering with Rab22b impairs TGN-to-endosome trafficking 153, disrupts the distribution ...

The author demonstrates that deficiency or pharmacological inhibition of O-glcNac transferase (OGT) enhances tumor immunity in colorectal cancer models. This useful study unveils that OGT deficiency ...

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.

Macroautophagy/autophagy is an intracellular degradation pathway that has an important effect on both healthy and diseased pancreases. It protects the structure and function of the pancreas by ...

They also assist with applications, and decision-making, and come with an alternative offer and financial support. At the University of Birmingham, we run Pathways to Birmingham which is a suite of ...

Her research looks at how nurses can be better supported to stay in a profession that is forecast to have an undersupply of 70,000 by 2035. With surging demand for data analytics professionals ...