However, severe cutaneous adverse reactions have been reported, most frequently not only drug rash with eosinophilia and systemic syndrome but also rare Stevens-Johnson syndrome and toxic epidermal ...

Date/Time: Tuesday, March 11, 2025, at 1:40 p.m. Eastern Time ...

Zongertinib, an investigational treatment for HER2-mutant advanced NSCLC, has received FDA priority review, showing positive ...

Toxic Epidermal Necrolysis (TEN) is a severe skin-mucosal reaction induced by medications, commonly characterized by blister formation and widespread epidermal ...

The risk for cardiovascular mortality in survivors of Stevens-Johnson syndrome and toxic epidermal necrolysis peaks within ...

Figure 1: Transgene expression and phenotype. Figure 2: K14.MYC2 mice exhibit impairment in wound healing. Figure 3: K14.MYC2 primary keratinocytes exhibit a defect in migration. Figure 4: K14 ...

Abstract: Electrophysiological disorders are serious and life-threatening conditions but their prevention can be improved with advanced on-skin and implantable biomedical sensors. These sensors are ...

Dysregulation of mTOR signaling underlies the pathogenesis of skin diseases, including psoriasis and skin cancer. In this review, we discuss the role of epidermal mTOR signaling activity and function ...

First identified by Stevens and Johnson in 1922, SJS and TEN are now recognized as disorders with a continuum of severity, from milder forms (SJS) to the most severe (TEN). SJS/TEN is associated with ...

Escalating concerns over impending tariffs and President Trump's foreign policies have fueled uncertainty and instability in ...