extracellular matrix degradation and vessel wall inflammation, all of which are hallmark features of abdominal aortic aneurysm pathogenesis. We present Spatial Modeling Algorithms for Reactions ...

The extracellular matrix (ECM), composed of a meshwork of proteins and proteoglycans, is a critical regulator of spine and synapse stability and plasticity. While the role of ECM receptors in spine ...

Furthermore, physical properties such as matrix viscoelasticity, extracellular fluid viscosity ... which marks HIF-2α for ubiquitin-mediated degradation via Von Hippel-Lindau (VHL), an E3 ubiquitin ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Emerging treatments include engineered immune cells and antibody therapies that direct the immune system’s attention toward prostate cancer. The Role of the Extracellular Matrix (ECM) in Cancer ...

the evolution and counteraction of necroinflammation and formation and degradation of extracellular matrix have been published with largely unconfirmed, impeached or even disproved associations.

Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or ... an array of changes including degradation of the normal ECM of liver ...

He noted that other assays studied in pancreatic cancer have only examined a handful of samples. "When they publish a second ...