A protein has many identities and one of them depends on the arrangement of its amino acids in the three dimensions of space — in other words, its 3D structure. And scientists have spent decades ...
Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...
Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...
While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they now discovered that these motors also put significant twists into the loops that they form.