This study demonstrates the development of PAGERs (programmable antigen-gated engineered receptors), combining antigen ...

结果显示，虽然AlphaFold3在预测整体GPCR骨架结构方面比AlphaFold2表现出更好的性能，但在配体（尤其是离子、多肽和蛋白质）结合方面，预测结果与实验结果之间仍然存在显著差异。该研究还评估了预测结构在各种配体类型中的准确性，量化了结合口 ...

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known ...