This study demonstrates the development of PAGERs (programmable antigen-gated engineered receptors), combining antigen ...

A team of scientists led by Professor Annette Beck-Sickinger from the Institute of Biochemistry at Leipzig University has ...

Researchers have identified a natural substance, hederagenin, that blocks the NPFFR1 receptor, a protein involved in pain perception in the brain and spinal cord.

“It turned out to be especially productive for solving the structure of G-proteins coupled to their receptors,” he says. As well as the leap from X-ray crystallography to cryo-EM, “emerging ...

Treatment delivered directly to the placenta restores normal blood pressure in mice, a way to make custom cellular switches, and a milestone for quantum computing.

Brain age gap (BAG) is a useful metric because it predicts one’s age-adjusted vulnerability to a range of neurological disorders, such as AD, dementia, and stroke. Although brain age may indeed ...

结果显示，虽然AlphaFold3在预测整体GPCR骨架结构方面比AlphaFold2表现出更好的性能，但在配体（尤其是离子、多肽和蛋白质）结合方面，预测结果与实验结果之间仍然存在显著差异。该研究还评估了预测结构在各种配体类型中的准确性，量化了结合口 ...

When combined with venetoclax and azacitidine (standard-of-care treatments for AML), STX-0712 improved therapeutic efficacy in 60% of patient samples by differential targeting both CCR2-positive ...

The hotspot at chr3q28 sits between the GMNC and osteocrin (OSTN) genes. They are involved in DNA replication and dendritic ...

Artelo Biosciences (NASDAQ:ARTL – Get Free Report)‘s stock had its “buy” rating reiterated by investment analysts at HC Wainwright in a research note issued on Monday,Benzinga reports. They presently ...

There’s been something of a sea change in the economic outlook for 2025, in the aftermath of last month’s election. The ...