2018b). The industrial requirement of high-quality natural fiber demands for its quality improvement. With the advancement of technology and emergence of new tools for uncovering the genome at gene ...

New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver ...

Syros Pharmaceuticals, Inc. (NASDAQ:SYRS) (the “Company”) today announced that its Board of Directors (the “Board”) has approved and the Company inten ...

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

High dose and low dose of TSHA-102 continue to be generally well tolerated with no treatment-related SAEs or DLTs in all pediatric, adolescent ...

Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

the team employed CRISPR-Cas9 gene editing to label the MFN1 and MFN2 proteins within the cell, without resorting to artificial overexpression. This approach allowed them to study mitofusins under ...