TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...

A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development ...

Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced ...

New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver ...

High dose and low dose of TSHA-102 continue to be generally well tolerated with no treatment-related SAEs or DLTs in all pediatric, adolescent ...

High dose and low dose of TSHA-102 continue to be generally well tolerated with no treatment-related SAEs or DLTs in all pediatric, adolescent and adult patients treated (high dose, n=6; low dose, n=4 ...

New therapies for managing aging could emerge from research into a new gene, which scientists have identified as a key driver ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma ...

Mutations in serine-threonine kinase 11 (STK11) and liver kinase B1 (LKB1) are associated with disease progression in ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

A Potential Solution for Neurodegenerative Diseases. Open Access Library Journal, 12, 1-16. doi: 10.4236/oalib.1112714 . Alzheimer’s Disease (AD), a complex neurodegenerative condition, significantly ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...