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Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...

Other groups of rats were used for additional analyses of gene and protein expression; these included rats dosed with AAVlac or the control vector AAVluc (expressing luciferase). These rats were ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

SPK-9001 is a novel, investigation vector containing a bio-engineered adeno-associated virus (AAV) capsid (protein shell) and a high-activity human coagulation FIX gene. The purpose of this gene ...

Cell and gene therapy is the hottest area in biotech at the moment, and Gilead’s $11.9bn acquisition of Kite Pharma in October has been followed by Celgene’s $9bn buyout of Juno Therapeutics.

The purpose of this study was to define unique gene expression profiles in muscle biopsies from patients with MSA-positive ... for classifying muscle biopsies into each type and MSA-defined subtype of ...

and the Integrated Microscopy Core (DK56338 and CA125123) with assistance from BCM's Gene Vector Core.

Pfizer’s decision to halt further marketing of Beqvez is further sign of the sparse patient interest in gene therapies for the bleeding condition. Rapid scientific advances have put the gene therapy ...

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