Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...

Other groups of rats were used for additional analyses of gene and protein expression; these included rats dosed with AAVlac or the control vector AAVluc (expressing luciferase). These rats were ...

Credit: Andrey_Popov / Shutterstock. Boehringer Ingelheim, the UK Respiratory Gene Therapy Consortium (GTC), IP Group and Oxford BioMedica (OXB) have commenced the Phase I/II LENTICLAIR 1 trial of ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Vincent Gaynor remembers, almost to the minute, when he realized his part in birthing the breakthrough gene therapy Zolgensma ...

and the Integrated Microscopy Core (DK56338 and CA125123) with assistance from BCM's Gene Vector Core.

Thermo Fisher is cutting the headcount at two of its US facilities by 300 as the company continues to overhaul its viral vector manufacturing output ... closing its biologics development and cell ...

The therapy consists of autologous CD34+ stem and progenitor cells modified with a lentiviral vector encoding the WAS gene. The rare disorder affects platelet production and immune system function, ...

Construction on Gene Autry and SR 111 has caused distress for drivers all week. News Channel 3's Luis Avila spoke with motorists impacted and is holding officials accountable on the impact ...

Pfizer’s decision to halt further marketing of Beqvez is further sign of the sparse patient interest in gene therapies for the bleeding condition. Rapid scientific advances have put the gene therapy ...

The study includes two cohorts receiving two doses, followed by an expansion cohort at the chosen dose. SENS-501 is stated to introduce the OTOF gene’s functional copy into the hair cells of the inner ...