脊椎炎的引发因素众多，主要有遗传因素、感染因素、自身免疫因素、环境因素、外伤与劳损等。 1. 遗传因素：遗传在脊椎炎的发病中起着重要作用。研究表明，某些基因与脊椎炎的易感性密切相关。例如，人类白细胞抗原B27（HLA - ...

Patients with ankylosing spondylitis and IBD exhibit distinct clinical and radiographic features, compared against those without comorbid IBD.

Recognizing psoriasis and psoriatic arthritis (PsA) in non-White patients is the first step toward providing more equitable care for those of all backgrounds with PsA, according to Rebecca Haberman, ...

脊柱关节炎（SpA）是一组以炎性关节炎为特征的疾病，包括强直性脊柱炎、银屑病性关节炎、反应性关节炎和关节炎相关的炎性肠病。虽然脊柱关节病的病因尚不清楚，但它被认为是一种涉及遗传和环境因素的自身免疫性疾病。遗传效应的部分原因是与人类白细胞抗原(HLA) B27基因的紧密联系，B27编码了主要的组织相容性复合体(MHC) ...

强直性脊柱炎（AS）是一种慢性、进展性风湿免疫性疾病，主要影响脊柱和骶髂关节，常伴随持续的炎症反应，严重时可能导致关节融合和脊柱僵硬。广州作为南方的重要城市，拥有丰富的医疗资源与先进的治疗技术，越来越多的患者通过精准诊疗与科学管理获得了病情的有效控制 ...

PORTLAND, OR, UNITED STATES, February 15, 2025 /EINPresswire / -- Ankylosing spondylitis (AS) is a chronic inf ...

While the genetic association of AS with the major histocompatibility molecule HLA-B27 has been known for almost five decades (2), the mechanistic link remains elusive. Like several other complex ...

apr.aphp.fr Objective To estimate the prevalence of spondyloarthritis (SpA) in reference to HLA-B27 in the French population. Methods In 1989, 20 625 employees of the French national gas and ...

Clinical variables included demographics, smoking, comorbidities, family history, extra-articular manifestations, medications, peripheral and axial symptoms, musculoskeletal and skin examination ...

Figure 3: Pattern of the timing of HIV CTL escape in relation to emergence of different HLA-B57- and HLA-A2-restricted CTL specificities. The consequence of transmission of escape variants is ...

This inflammatory form of arthritis—which can cause back pain in people under the age of 45—can take more than a decade to be diagnosed.