The hematopoietic stem cell (HSC) niche is a specialized microenvironment, where a complex and dynamic network of interactions across multiple cell types regulates HSC function. During the last years, ...

Hematopoietic stem cells (HSCs) undergo self-renewal and differentiation in the bone marrow, which is tightly regulated by cues from the microenvironment. The gut microbiota, a dynamic community ...

in the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy, a life-threatening complication in both adult and pediatric hematopoietic stem cell transplantation.

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

In stem cell research, cell separation identifies and grows certain cell types, such as hematopoietic stem cells. Due to enhanced comprehension, a growing proportion of people residing in ...

The novel drug CT-179 ... How Healthy Stem Cells Turn Into Oral Cancer Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into ...

This study defines the RNA m 6 A methylome of skeletal cell populations and reveals the role of METTL3-dependent regulation of FEM1B-GLI1 module in maintaining the function of skeletal stem cells ...

The Oregon Stem Cell Center conducts basic and applied research in the field of Stem Cell Biology with the long term goal to harness the properties of stem cells for regenerative medicine and cell ...

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On track to report initial data from Phase 1/2 clinical trial of PM359 for p47phox CGD in 2025 -- -- IND-enabling studies ongoing for PM577 for Wilson's Disease; expect to file IND and/or CTA in ...