作为HIV感染中缺陷性T淋巴细胞的替代标志物，CD4:CD8比值近年来再次引起了广泛关注。CD8细胞计数的增加导致该比值降低，在接受有效治疗且病毒学抑制良好的个体中甚是明显，这可能是免疫异常和慢性炎症显著的亚群的特征。研究表明，接受抗逆转录病毒治疗 ...

Human single cell RNA-sequencing reveals a targetable CD8 + exhausted T cell population that maintains mouse low-grade glioma growth With the emergence of immune checkpoint inhibitor therapies for ...

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung ...

MDNA11 shows significant survival benefits in preclinical glioblastoma models, expanding CD8 + T and NK cells Bizaxofusp selectively targets human tumor cells and immune-suppressive cells, enhancing ...