Nov. 29, 2024 — For pregnant women, exposure to fine particulate air pollution (PM2.5) was associated with altered immune responses that can lead to adverse birth outcomes, according to a new ...
This limits the wide impact of this study but can be used as a starting point to examine sex- and age differences in the transcriptome due to alternative splicing. Complex diseases often exhibit ...
The agency is also evaluating if there's a need for further regulatory action based on reports of hematologic malignancies from clinical trials of the therapy.
SPK-9001 is a novel, investigation vector containing a bio-engineered adeno-associated virus (AAV) capsid (protein shell) and a high-activity human coagulation FIX gene. The purpose of this gene ...
Exegenesis Bio, a clinical stage global gene therapy company is pleased to announce that US FDA has granted Orphan Drug Designation ("ODD") to EXG110, a novel gene therapy for Fabry disease, a rare ...
Introduction and Objectives Gene therapy for cystic fibrosis is approaching clinical trials. Using a lentiviral vector pseudotyped with Sendai virus fusion and hemagglutinin ... and measure protein ...
In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ...